Recurrent syncope in a patient with Andersen’s syndrome

March 2002    Volume 9, Issue 3   Br J Cardiol 2002;9:168-70

Authors:
Wayne R Arthur, Gerry C Kaye, Robert F Mueller

Recurrent syncope in a patient with Andersen’s syndrome Wayne R Arthur, Gerry C Kaye, Robert F Mueller Most common inherited diseases with cardiac involvement are associated with structural abnormalities of the heart and/or great vessels. Discussions of inherited cardiac electrophysiological abnormalities were once limited to Jervell and Lange-Nielsen syndrome and Romano-Ward syndrome. Subsequently, other genetically distinct arrhythmogenic cardiovascular disorders have been discovered.1 These result from mutations in the fundamental cardiac ion channels that orchestrate the action potential of the human heart. Most of these genetic channelopathies are depicted by marked QT prolongation on the electrocardiogram.

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