Serious interaction between digoxin and warfarin

June 2002    Volume 9, Issue 6   Br J Cardiol 2002;9:356-7

Authors:
Arpandev Bhattacharyya, Manju Bhavnani, David James Tymms

Drug interaction with warfarin is a common cause of loss of anticoagulant control. An interaction between warfarin and digoxin has not previously been documented in the British National Formulary or datasheet. We report a case of digoxin toxicity responsible for prolongation of the INR to more than 10.

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