Stent thrombosis and antiplatelet therapy: a review of 3,004 consecutive patients in a single centre

September 2007    Volume 14, Issue 4   Br J Cardiol 2007;14:234-6

Authors:
Nick Curzen, Geraint Morton, Alex Hobson, Iain Simpson, Alison Calver, Huon Gray, Keith D Dawkins

Stent thrombosis (ST) is an uncommon but serious complication of percutaneous coronary intervention (PCI), and is associated with the discontinuation of antiplatlet therapy. In a retrospective study of ST cases during a two-year period of the Wessex Regional Cardiac Unit, 3,004 (1,661 emergency and 1,343 elective) patients underwent PCI between November 2003 and October 2005. There were 25 episodes of ST occurring in 22 patients (overall incidence of ST is 0.83%). There were two (8%) cases of acute ST, eight (32%) of sub-acute ST and 15 (60%) of late or very late ST (five cases between six and 12 months and one case more than one year post-procedure). In the late and very late ST group only one patient was taking dual antiplatelet therapy.

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