2005, Volume 12, Issue 05, pages 321-404

The National Service Framework for Coronary Heart Disease (CHD) stated that individuals at greatest risk of CHD should be identified. This category included those with...

Two surveys were carried out to look at statin prescribing in UK general practice. The first was a study of the Mediplus prescribing database in...

Meig’s syndrome is a condition in which an ovarian tumour (usually a fibroma) is associated with ascites and pleural effusion. It resolves after resection of...

The recent withdrawal of rofecoxib, a COX-2 inhibitor, has focussed attention on the use of COX-2 inhibitors and other non-steroidal anti-inflammatory drugs (NSAIDs) in patients...

Selective inhibition of COX-2 preferentially inhibits the production of prostaglandins responsible for vasodilation and inhibition of platelet aggregation. This potentially creates a pro-thrombotic state. This...

Multiple randomised controlled trials have unequivocally shown that lowering low-density lipoprotein cholesterol (LDL-C) results in a predictable reduction of coronary events and it appears that...

The National Service Framework for Coronary Heart Disease recommended in 2000 that cardiac rehabilitation (CR) should be offered to 85% of patients recovering from myocardial...

Structured exercise, as a therapeutic intervention, is central to cardiac rehabilitation (CR). Following myocardial infarction (MI), cardiac autonomic activity becomes disordered, often resulting in loss...

The provision of cardiac rehabilitation (CR) services in the UK was surveyed in March 2003. Three hundred questionnaires were sent to Directors of Public Health...

The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) reported the final results of its blood pressure lowering arm at the European Society of Cardiology (ESC) Annual meeting...

Heart failure affects over 750,000 people in the UK and 65,000 new cases are diagnosed every year. It carries a poor prognosis with a population-based...