Protecting the heart by postconditioning

Br J Cardiol 2007;14:129-30 Leave a comment
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Coronary heart disease (CHD) is the leading cause of death in the UK (accounting for 105,000 deaths in 2004) and exerts a huge burden, both on our healthcare system (around £3,500 million in 2003) and on our economy (£7.9 billion per year). Following an acute myocardial infarction (AMI), the 30-day mortality remains significant at around 10%, despite successful reperfusion therapy, instituted by either thrombolysis or primary percutaneous coronary intervention (PCI), paving the way for novel cardioprotective strategies to be developed.

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