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Tag Archives: major adverse cardiovascular events (MACE)

October 2025 Br J Cardiol 2025;32(4) doi:10.5837/bjc.2025.044 Online First

Comparative efficacy of drug-coated balloons versus drug-eluting stents in treating de novo CAD in ACS

Sushant Saluja, Fahmida Mannan, Maaham Saleem, Magdi El-Omar, Amjad Khanfar, Anusha Singh, Freidoon Keshavarzi, Mohammed Alawami

Abstract

Introduction The management of coronary artery disease (CAD) in patients presenting with acute coronary syndromes (ACS) poses a significant challenge in interventional cardiology.1 As clinical practice evolves, the imperative to compare the outcomes of drug-coated balloons (DCB) and drug-eluting stents (DES) has gained prominence, particularly considering the distinct pathophysiological characteristics and risks associated with ACS.2 Insights from the BASKET-SMALL 2 trial, the largest randomised clinical trial assessing DCB versus DES for small-vessel CAD, provide pivotal evidence in this area. This prespecified analysis yielded three signifi

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