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June 2021 Br J Cardiol 2021;28(3) doi:10.5837/bjc.2021.028

50th anniversary of Ionescu’s pericardial heart valve concept

Sunil Ohri, Suvitesh Luthra

Abstract

Figure 1. The Ionescu-Shiley pericardial xenografts Material choice It was a stroke of Ionescu’s genius, industry and tenacity that among all the materials available at the time, such as polyurethane, ivalon, fascia lata and dacron, he finally chose glutaraldehyde-treated bovine pericardium to construct his valves. To arrive at this point Marian Ionescu had already been on a 14-year journey of invention, which started in 1957 and included the three-pronged coronet design of the aortic valve used to this day. Over the last five decades, we have now realised that the pericardium has four unique defining characteristics – pliability, durabil

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