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Tag Archives: venous thromboembolism (VTE)

Insights in the treatment and prophylaxis of venous thromboembolism

July 2019 Br J Cardiol 2019;26(suppl 2):S15–S19 doi:10.5837/bjc.2019.s10

Insights in the treatment and prophylaxis of venous thromboembolism

Jecko Thachil

Abstract

Introduction Venous thromboembolism (VTE) is a common source of morbidity and mortality: for example, the annual incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) in the UK have been estimated as 1/10,000 and 3–4/10,000 individuals, respectively, although the latter figure is considered to be an underestimate.1,2 The majority of cases of VTE occur during or following hospitalisation, and VTE has been described as the primary source of avoidable mortality in hospital;3 accordingly, more than 95% of such patients received a VTE risk assessment in 2016.4 Vitamin K antagonists (VKA), the standard of care for managing VTE for

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Insights from primary care: opportunities and challenges

July 2019 Br J Cardiol 2019;26(suppl 2):S20–S23 doi:10.5937/bjc.2019.s12

Insights from primary care: opportunities and challenges

Nigel Rowell

Abstract

Introduction Three important lines of evidence have informed the debate on optimal anticoagulation for people at risk of stroke: Meta-analyses have generally supported the findings from the ENGAGE-AF TIMI-481 and Hokusai-VTE2 trials, in terms of comparable efficacy and reduced bleeding risk with non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients at risk of stroke, or with acute venous thromboembolism (VTE), respectively.3-8 The randomised Birmingham Atrial Fibrillation Treatment of the Aged Study (BAFTA) trial confirmed the superiority of anticoagulation versus aspirin in elderly patients with atrial fibrillati

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