2004, Volume 11, Supplement 2: Improved cardiovascular risk reduction: the evidence for raising HDL cholesterol

January 2004 Br J Cardiol 2004;11(Suppl 2):S1-S20

Improved cardiovascular risk reduction: the evidence for raising HDL cholesterol

Gerd Assmann, Peter Libby, Christie Ballantyne, John Betteridge, John Chapman

Abstract

High-density lipoprotein (HDL) cholesterol is an important molecule in cardiovascular disease. In myocardial infarction (MI) survivors, low levels of HDL are commonly found. For example, in the Prospective Cardiovascular Münster (PROCAM) study, coronary angiography was performed, and HDL and lowdensity lipoprotein (LDL) levels were measured, in 1,293 MI survivors and 11,402 controls. Lipoprotein measurements show that the LDL level was on average 50 mg/dl higher in MI survivors aged 30–39 years as compared to age-matched controls....

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