Lipids

This programme is not currently eligible for CPD accreditation. It has been independently written by leading UK physicians, and has been endorsed by HEART UK – The Cholesterol Charity.

Programme-AnginaWelcome to this modular e-learning programme: dyslipidaemia in clinical practice.

The association of high cholesterol levels and increased risk of coronary heart disease (CHD) was recognised from epidemiological studies conducted in the 1950s and 1960s. At the time, treatment options to reduce cholesterol were limited to bile acid binding resins, fibrates and nicotinic acid. The hypothesis that cholesterol reduction could reduce CHD had not been thoroughly tested. It was not until the late 1980s, with the introduction of the HMG-Co-A reductase inhibitors (statins) that LDL-cholesterol lowering was effective in the prevention of cardiovascular disease and mortality (see ‘Lipid disorders,’ Nicholls P, Young I. Oxford Cardiology Library 2009).

In this modular programme we will first be introduced in Module 1 to lipid metabolism and its role in atherosclerosis. Module 2 will discuss how to assess cardiovascular risk and why management of dyslipidaemia is important, Module 3 will review the clinical diagnosis of dyslipidaemia, while Module 4 will look at the role of individual drugs. Modules will be complimented by case studies.

Each module will have a series of multiple-choice questions.

Dr Dermot Neely, Consultant in Clinical Biochemistry and Metabolic Medicine, Royal Victoria Infirmary, Newcastle upon Tyne
Dr Mike Khan, Chief Medical Officer, Silence Therapeutics plc
Dr David Thompson, Clinical Research Fellow, International Centre for Circulatory Health, Imperial College London, London

Lipids module 1: lipid metabolism and its role in atherosclerosis

Released 9 July 2015   Programme: Lipids 1 CPD/CME credit

Lipids module 1: lipid metabolism and its role in atherosclerosis
  • Understand the essential lipid fractions that form the building blocks of lipid physiology
  • Review the mechanisms which facilitate lipid transport between tissues
  • Describe the role of lipid particles in atherogenesis
  • Understand clinically important cholesterol measurements

Lipids module 2: cardiovascular risk

Released 9 July 2015   Programme: Lipids 1 CPD/CME credit

Lipids module 2: cardiovascular risk
  • Define the concept of ‘risk factors’
  • Understand the need for risk assessment and screening
  • Utilise ‘risk engines’ and scoring systems
  • Assess which patients to exclude from standard risk assessment

Lipids module 3: clinical diagnosis of dyslipidaemia

Released 9 July 2015   Programme: Lipids 1 CPD/CME credit

Lipids module 3: clinical diagnosis of dyslipidaemia
  • Review the clinical diagnosis of dyslipidaemia
  • Use clinical findings and abnormalities of the lipid profile to identify and diagnose patients with dyslipidaemia
  • Understand components of the lipid profile and how they are measured and calculated
  • Recognise the role of lipid profiling in coronary risk assessment including measurement of lipoprotein(a)

Lipids module 4: treatment of dyslipidaemia

Released 9 July 2015   Programme: Lipids 2 CPD/CME credits

Lipids module 4: treatment of dyslipidaemia
  • Assess evidence for lipid lowering
  • Review which patients are eligible for lipid management
  • Utilise lifestyle (diet and exercise) interventions
  • Define drug classes for the modification of lipids