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MI with multiple distal occlusions associated with use of the synthetic cannabinoid 5F-AKB48

March 2015 Br J Cardiol 2015;22:40 doi:10.5837/bjc.2015.012

MI with multiple distal occlusions associated with use of the synthetic cannabinoid 5F-AKB48

Jason L Walsh, Benjamin H L Harris, Nicholas Ossei-Gerning

Abstract

Introduction In recent years, the recreational use of synthetic cannabinoids has been gaining global popularity.1-5 Case reports have emerged associating these compounds with a number of adverse effects, including: embolic-appearing ischaemic strokes,6 seizures7 and acute kidney injury.8 In addition, myocardial infarction (MI) has been associated with synthetic cannabinoid use in teenagers.9,10 However, no cases have demonstrated abnormal coronary angiography. There are numerous synthetic cannabinoids, including JWH-018, JWH-073, HU-210, CP 47,497, JWH-081, JWH-122, JWH-210, and newer compounds are regularly being developed.4 A proportion of

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