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Tag Archives: aldosterone antagonists

December 2020

Sacubitril-valsartan benefits in cancer therapy-related cardiac dysfunction

BJC Staff

Abstract

The patients who developed cardiotoxicity were treated with beta blockers (carvedilol), angiotensin-converting enzyme inhibitors (enalapril) or angiotensin receptor blockers (valsartan), aldosterone antagonists (eplerenone), digitalis and diuretics (furosemide), as needed. When patients remained symptomatic and met the PARADIGM-HF inclusion criteria, sacubitril/valsartan was started instead of enalapril or valsartan. Results showed that sacubitril/valsartan therapy produced an improvement in ventricular remodelling, diastolic dysfunction, and on symptoms, reflected in the New York Heart Association class and the six-minute walk test. The auth

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October 2002 Br J Cardiol 2002;9:533-7

Aldosterone antagonism: new ideas, new drugs

Mike Schachter

Abstract

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