August 2012 Br J Cardiol 2012;19:107–10
BJCardio Staff
The study, published on July 18 in PLoS One, was conducted by Dr David Wald (Wolfson Institute of Preventive Medicine, London) and colleagues. The polypill used contained three antihypertensive medications – the calcium antagonist, amlodipine 2.5 mg; the angiotensin-receptor blocker, losartan 25 mg; and the diuretic, hydrochlorothiazide 12.5 mg – in addition to the cholesterol-lowering agent simvastatin 40 mg. In the study, 86 individuals were randomised to the polypill or placebo for 12 weeks. They then crossed over and took the other treatment. Mean systolic blood pressure was reduced by 17.9 mmHg, diastolic pressure was reduced by 9.8
January 2005 Br J Cardiol 2005;12:65-70
FD Richard Hobbs, Peter Irwin, Janet Rubner
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April 2002 Br J Cardiol 2002;9:215-20
Philip MW Bath
No content available
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