August 2024 Br J Cardiol 2024;31:115 doi:10.5837/bjc.2024.035
Leila Bigdelu, Seyed Mahdi Majidi Talab, Muhammad Usman Shah, Parisa Niknafs, Majid Khadem Rezaiyan, Syed Yaseen Naqvi
Introduction The World Health Organisation (WHO) defines obesity as “abnormal or excessive fat accumulation that may impair health” and classifies obesity based on body mass index (BMI), with those with a BMI of 25–30 kg/m2 termed as overweight and those with BMI over 30 kg/m2 defined as obese.1,2 Obesity has reached pandemic levels in the last 50 years.3 One and a half billion people over the age of 20 in the world are thought to be overweight or obese.4 Obesity is associated with low-grade chronic inflammation leading to insulin resistance, which may progress to diabetes mellitus.5 Moreover, fatty liver disease, systemic hypertension
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