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The SERVE-HF study: investigating the impact of central sleep apnoea on heart failure

April 2013 Br J Cardiol 2013;20:50–1 doi:10.5837/bjc.2013.011 Online First

The SERVE-HF study: investigating the impact of central sleep apnoea on heart failure

Martin Cowie

Abstract

An overlooked form of SDB Professor Martin Cowie Another form of sleep apnoea – central sleep apnoea with Cheyne Stokes respiration (CSA-CSR) – has received less in-depth investigation than OSA. Nonetheless, it carries significant importance, particularly in heart failure patients. Moderate-to-severe forms have been reported to occur in up to 50% of chronic heart failure patients.4-7 Unlike OSA patients, whose loud night-time snores are punctuated with dramatic apnoeic episodes, CSA-CSR patients exhibit a different style of breathing. In this patient group, night-time breathing follows a waxing and waning pattern in which successive breat

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