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Atherosclerotic peripheral artery disease: the growing challenge to improve life and limb

March 2020 Br J Cardiol 2020;27(suppl 1):S4–S8 doi:10.5837/bjc2020.s02

Atherosclerotic peripheral artery disease: the growing challenge to improve life and limb

Matthew A Popplewell, Owain Fisher, Ruth A Benson, Andrew Garnham

Abstract

Introduction Currently, worldwide, there is an impending epidemic of symptomatic peripheral artery disease (PAD). This is largely due to the increasing prevalence of risk factors such as: smoking, diabetes, high blood pressure (BP), cholesterol, and end-stage renal disease (ESRD). In the developed world this is largely due to an epidemic of diabetes and obesity. There is a wide spectrum of PAD that ranges from asymptomatic disease through to chronic limb-threatening ischaemia (CLTI). Depending upon income and region, the number of sufferers with PAD has increased by 13–25% during the last decade, accounting for 202 million people worldwide

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