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Tag Archives: chronic obstructive pulmonary disease (COPD)

October 2025 Br J Cardiol 2025;32:123–4 doi:10.5837/bjc.2025.043

COPD and CVD: the dangerous duo reshaping cardiopulmonary care

Ismail Sooltan, Aqib Khan, Sudantha Bulugahapitiya

Abstract

Mechanisms linking COPD and CVD The interrelationship between COPD and CVD is underpinned by several interconnected pathophysiological mechanisms.3,5 Chronic systemic inflammation, a hallmark of COPD, extends beyond the lungs, contributing to atherosclerosis and cardiovascular dysfunction.5 Elevated levels of inflammatory markers such as C-reactive protein and interleukin-6 are observed in both conditions, suggesting a shared inflammatory pathway.6 Oxidative stress, another key feature of COPD, leads to endothelial dysfunction and vascular damage, accelerating the progression of CVD.7 This is exacerbated by shared risk factors, particularly s

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