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Unlocking the potential of NOACs

December 2014 Br J Cardiol 2014;21(suppl 2):S1–S7

Unlocking the potential of NOACs

Mr Sotiris Antoniou, Dr Chris Arden, Dr Jan Beyer-Westendorf, Dr David Hargroves, Dr Terry McCormack, Professor Gordon McInnes, Dr Raj Patel, Oliver Segal

Abstract

When the NOACs (novel oral anticoagulants) were introduced over three years ago, they promised to revitalise the management of conditions such as atrial fibrillation (AF), venous thromboembolism (VTE) and thromboprophylaxis after major joint replacement surgery. Rivaroxaban is currently available in multiple indications, including (but not limited to): prevention of stroke and systemic embolism in adult patients with non-valvular AF, treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and the prevention of recurrent DVT and PE in adults. For decades anticoagulant therapy in these conditions had relied on the vitamin K antagon

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