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September 2010 Br J Cardiol 2010;17:245–8

Ictal bradycardia and asystole associated with intractable epilepsy: a case series

Elijah Chaila, Jaspreet Bhangu, Sandya Tirupathi, Norman Delanty

Abstract

Introduction Heart rhythm changes are common during seizures, even those seizures not associated with convulsive activity. Most studies report tachycardia, a heart rate increase of more than 10 beats per minute above the baseline, as the most common rhythm abnormality occurring in 64–100% of temporal lobe seizures.1,2 By contrast, ictal bradycardia has been reported in less than 6% of patients with complex partial seizures.3,4 The ictal bradycardia syndrome occurs in those with established epilepsy when epileptic discharges disrupt normal cardiac rhythm leading to a decrease in heart rate of more than 10 beats per minute below the baseline.

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