Tag Archives: IgG4-related disease

Introduction Immunoglobulin G4-related disease (IgG4-RD) is an immunologic fibro-inflammatory systemic disease that may affect different parts of the body in different ways. The involved organs or structures are infiltrated by inflammatory IgG4-positive plasma cells, which, if untreated, result in fibrosis and permanent organ damage.1 Case summary A 54-year-old woman presented with recurrent breast cancer within 10 years of her original diagnosis. Her initial breast disease was a right-side ductal carcinoma in situ (DCIS) treated with lumpectomy, followed by radiation and tamoxifen. Her past history was significant for Graves’ disease, auto