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Tag Archives: in vitro diagnostics

July 2008 Br J Cardiol 2008;15:199-204–6

Cost-consequences analysis of natriuretic peptide assays to refute symptomatic heart failure in primary care

Michael A Scott, Christopher P Price, Martin R Cowie, Martin J Buxton

Abstract

Introduction Heart failure is a serious syndrome accounting for around 4% of UK general practitioner (GP) consultations in patients over 45 years.1 Diagnosis is complex with frequent co-existing symptoms; misdiagnosis may lead to inappropriate treatment and inefficient use of scarce healthcare resources.2 The National Institute for Health and Clinical Excellence (NICE) guidelines for chronic heart failure state that the 12-lead electrocardiogram (ECG) and/or natriuretic peptides tests (where available) may be used to help exclude heart failure.3 Abnormal ECGs are usually observed in heart failure cases, although in one study, around 20% of pa

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