Professor Klaus Parhofer
Lipoprotein (a)
The role of lipoprotein (a) [Lp(a)] was explored by Professor Klaus Parhofer (Ludwig Maximilians University, Munich, Germany). This is an independent risk factor in cardiovascular disease (CVD), with a causal link to atherosclerosis, myocardial infarction (MI), aortic valve stenosis and heart failure.
Of the different therapies that can be used to reduce elevated Lp(a), only apheresis shows a reduction in CVD events. Currently, the most important management strategy is to optimise all other CVD risk factors, particularly low-density-lipoprotein cholesterol (LDL-C). In patients with progressive CVD, de