Pathogenesis
With the advent of the iodinated contrast study came the complication of contrast-induced nephropathy (CIN), an increasingly recognised and discussed iatrogenic disease process seen with coronary angiography. As we become more invasive in our cardiac investigations, and coronary interventions become more widespread, coronary angiography is offered to more and more patients. Therefore, a better understanding of the treatment modalities aimed at minimising the risk of CIN has never been more important.
Figure 1. Aetiology of contrast-induced nephropathy
CIN is a direct hyper-acute tubular insult on the filtering mechanisms of the k