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Tag Archives: left pleuropericardial agenesis

Left pleuropericardial agenesis and coronary artery disease

August 2012 Br J Cardiol 2012;19:124–5 doi:10.5837/bjc.2012.023

Left pleuropericardial agenesis and coronary artery disease

Pankaj Kaul

Abstract

Introduction Left pleuropericardial agenesis is a developmental abnormality that results in the heart and the left lung sharing a common coelomic cavity. This abnormality manifests due to failure of mesodermal ingrowth from the lateral body wall to close off the left pleuropericardial canal and also the failure of development of the left pleuropericardial membrane. Although pre-operative diagnosis is very unusual, partial agenesis can precipitate catastrophic complications of chamber or appendage incarceration. Complete agenesis results in incompletely understood effects on the right ventricular geometry due to luxation of heart into an extre

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