January 2022 Br J Cardiol 2022;29:16–20 doi:10.5837/bjc.2022.003
Nicholas P Gall, Stephen James, Lesley Kavi
Introduction Postural tachycardia syndrome (PoTS) was first described in American Civil War soldiers,1 and subsequently in First World War soldiers.2 These early descriptions were published by some of the most eminent cardiologists of the time. It was defined formally as a syndrome in 1993,3 leading onto guidelines, more recently published by the Heart Rhythm Society 2015,4 and the Canadian Cardiovascular Society 2020.5 While we remain uncertain in detail about its underlying cause, it seems to be an abnormality in the regulation of the cardiovascular system causing excessive tachycardia on standing, with cardiovascular symptoms including ch
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