Tag Archives: NAFLD

I wish to comment on recent work linking non-alcholic fatty liver disease (NAFLD) with a high risk of cardiovascular mortality.1,2 One issue which has not been addressed in these studies is the potential role of coenzyme Q10 (CoQ10) deficiency in the pathogenesis both of NAFLD and subsequent cardiovascular disease. CoQ10 is a vitamin-like substance that plays a key role in the biochemical process supplying all cells with energy. CoQ10 also has antioxidant and anti-inflammatory action. An adequate supply of CoQ10 is particularly important in tissues with a high energy requirement, such as the heart and liver. Most of the body’s daily req

FH: improving detection in primary care The launch of the NICE (National Institute of Health and Care Excellence) guidelines for familial hypercholesterolaemia (FH) heralded great optimism for improving detection rates in primary care.1 Even with new research showing that FH is more common than previously thought,2  still around 80% of patients are not recognised. Novel detection approaches are clearly needed. Professor Nadeem Qureshi (University of Nottingham) presented preliminary findings from six GP centres taking part in FAMCHOL (Feasibility of Improving Identification of Familial Hypercholesterolaemia in General Practice: Intervention