Tag Archives: NVUGIB

Of the serious complications of gastrointestinal ulcers (bleeding, perforation, obstruction, and sometimes death), non-variceal upper gastrointestinal bleeding (NVUGIB) remains the commonest. These days it is mostly seen in association with the use of antithrombotic drugs (ATDs), particularly low-dose aspirin (75–325 mg/day), given for vascular protection.1 Nicorandil is a vasodilator that acts as a nitrate and K+ATP channel agonist. It is used in many countries worldwide and is often added to ATDs in the management of angina. In light of some case reports, its manufacturer and the medicines advisors and regulatory agencies have issued caut