This website is intended for UK healthcare professionals only Log in | Register

Tag Archives: obstructive hypertrophic cardiomyopathy

October 2011 Br J Cardiol 2011;18:201-2 doi:10.5837/bjc.2011.001

Alcohol septal ablation for the relief of symptoms in obstructive HCM: a ‘coming of age’

Neha Sekhri, Peter Mills, Charles Knight

Abstract

HCM is conventionally understood as a cardiac disease inherited in an autosomal dominant fashion with incomplete penetrance. Over the past two decades, genetic research has established that HCM has considerable allelic and non-allelic heterogeneity. For the majority of patients, outside of its utility in pre-symptomatic screening, a genetic diagnosis has not made important contributions to clinical management. In large part, this is because most proband patients have apparently unique mutations, and because the fidelity between genotype and phenotype has been poor in families and for mutations studied thus far. Over the last 20 years, the di

| Full text
Close

You are not logged in

You need to be a member to print this page.
Find out more about our membership benefits

Register Now Already a member? Login now
Close

You are not logged in

You need to be a member to download PDF's.
Find out more about our membership benefits

Register Now Already a member? Login now