June 2026 Br J Cardiol 2026;33(suppl 1):S3 doi:10.5837/bjc.2026.s01
Christine Chiti, Kate Taylor, Seema Patel, Ben Laryea, Vincent Nicholas, Dr Jason N Dungu
Diagnosis of ATTR-CM can take years – by which time irreversible heart failure may have already occurred.2,8 hATTR-CM severely impairs quality of life, and median survival in advanced stages is typically only two to three years without timely intervention.2 The Genetic Link to Heart Failure Figure 1. Underlying Pathology of hATTR Caused by the p.V142I Variant9,10 Liver
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