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October 2021 Br J Cardiol 2021;28:153–4 doi:10.5837/bjc.2021.044

Analysis of the trend in community prescribing of RAAS inhibitors during the COVID-19 pandemic

Layla Guscoth, Sam Hodgson

Abstract

Introduction From December 2019, SARS-CoV-2, a novel coronavirus, sparked a global pandemic and rapid scientific responses to the new coronavirus 2019 (COVID-19) disease. Rapid identification showed the angiotensin-converting enzyme 2 (ACE-2) as the host receptor for SARS-CoV-2. Given this, concerns were raised that renin–angiotensin–aldosterone system (RAAS) inhibitors, such as ACE inhibitors and angiotensin-receptor blockers (ARBs), which may increase the expression of ACE‑2, could negatively influence COVID-19 outcomes. This led to significant media attention and anxiety about ongoing use of these medications. However, there has bee

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