Tag Archives: retinopathy

DIRECT results suggest increased regression of retinopathy in type 2 diabetes Three studies of the effect of candesartan on diabetic retinopathy produced mixed results in the first large-scale programme assessing the effect of an angiotensin receptor blocker on the incidence and progression of eye complications in patients with diabetes. The primary end points in the three DIabetic REtinopathy Candesartan Trials (DIRECT) were just missed. But investigators and independent clinicians argued the data were strong enough to influence clinical practice in secondary care although were insufficient to support a licence change. Professor Anthony Barn