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Tag Archives: SBP

September 2024 Br J Cardiol 2024;31(3) doi:10.5837/bjc.2024.040 Online First

Correspondence: Prevention of stroke

Oscar M P Jolobe with a response from Nimisha Shaji, Robert F Storey and William A E Parker

Abstract

The latter study enrolled 9,361 participants, of whom 4,683 were randomised to a goal SBP of <140 mmHg, and 4,678 were randomised to a goal SBP of <120 mmHg, the latter defined as intensive blood-pressure lowering. During 5.2 years of follow-up, intensive SBP lowering was associated with a 26% lower risk of developing new-onset AF (hazard ratio 0.74, 95% confidence interval 0.56 to 0.98, p<0.037). This effect was consistent among prespecified subgroups of participants stratified by age and sex.2 It is salutary to note that patients aged 60 years and older who have a life-expectancy of >3 years also benefit from intensive SBP lower

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