May 2008 Br J Cardiol 2008;15:123–30
Terry McCormack
ENHANCE controversy dominates meeting The controversial ENHANCE (Ezetimibe and Simvastatin in Hypercholesterolaemia Enhances Atherosclerosis Regression) trial of ezetimibe dominated the ACC meeting, with a special session held to discuss the results, which were simultaneously published in the New England Journal of Medicine. The 720-patient trial showed no benefit of ezetimibe when added to simvastatin 80 mg in slowing the progression of atherosclerosis in the carotid artery (as measured by intima media thickness (IMT) in patients with familial hypercholesterolemia (FH), despite the fact that there were significantly greater reductions in lo
July 2005 Br J Cardiol (Acute Interv Cardiol) 2005;12:AIC 49–AIC 53
Jeremy N Butts, Kenneth P Morgan, Kevin J Beatt
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