Tag Archives: sodium zirconium cyclosilicate (SZC)

Hyperkalaemia in heart failure HK is a potentially life-threatening electrolyte abnormality. There is no universal definition of HK; however, a serum level greater than 5.0–5.5 mmol/L is generally regarded as abnormal.4 The Swedish heart failure registry showed an increased mortality associated with abnormal serum potassium.5 Hypokalaemia is associated with increased long-term mortality, as opposed to HK’s association with increased short-term mortality.5 The incidence of HK in heart failure remains highly variable.4,6,7 In PARADIGM-HF, enalapril was compared with the combination drug sacubitril/valsartan. The latter had a hazard ratio of

Hyperkalaemia in heart failure HK is a potentially life-threatening electrolyte abnormality. There is no universal definition of HK; however, a serum level greater than 5.0–5.5 mmol/L is generally regarded as abnormal.4 The Swedish heart failure registry showed an increased mortality associated with abnormal serum potassium.5 Hypokalaemia is associated with increased long-term mortality, as opposed to HK’s association with increased short-term mortality.5 The incidence of HK in heart failure remains highly variable.4,6,7 In PARADIGM-HF, enalapril was compared with the combination drug sacubitril/valsartan. The latter had a hazard ratio o