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Tag Archives: subcutaneous implantable cardiac device (SICD)

Pacing supplement: Cardiac resynchronisation therapy – developments in heart failure management

October 2018 Br J Cardiol 2018;25(suppl 3):S12–S19 doi:10.5837/bjc.2018.s14

Pacing supplement: Cardiac resynchronisation therapy – developments in heart failure management

Francisco Leyva

Abstract

Professor Francisco Leyva Introduction Cardiac resynchronisation therapy (CRT) is a standard treatment for patients with heart failure (HF), impaired left ventricular (LV) function and a wide QRS complex. The therapy emerged following the recognition that disturbances in inter- and intra-ventricular conduction contribute to LV dysfunction. Since its first clinical use,1,2 robust evidence from randomised-controlled trials (RCTs) has supported its use in patients with severe and mild HF. In combination with defibrillation (CRT-D), CRT reduces mortality from pump failure and sudden, arrhythmic cardiac death (SCD). Since the last RCTs on CRT,3 th

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