May 2023 Br J Cardiol 2023;30(suppl 2):S10–S14 doi:10.5837/bjc.2023.s07
Muntaser Omari, Holli Evans, Azfar G Zaman
Background Sustained reduction of elevated cholesterol (particularly low-density lipoprotein cholesterol [LDL-C]) with currently available therapies is associated with reduced atherosclerotic cardiovascular (CV) events in both primary and secondary prevention.1 Nevertheless, some individuals continue to exhibit substantial residual CV risk, which is associated with higher concentrations of atherogenic cholesterol carried by circulating triglyceride (TG)-rich lipoproteins. The failure to reduce CV events through TG reduction in statin-treated patients with niacin, fibrates and a carboxylic acid formulation of omega-3 polyunsaturated fatty acid
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