Tag Archives: triglycerides

There is substantial evidence that a diet rich in fish results in lower levels of atherosclerosis. This has led to the hypothesis that fish oils, which are known to reduce triglyceride levels – an independent risk for cardiovascular events – might also reduce the level of cardiovascular disease possibly by lowering triglycerides. The open-label Japan EPA Lipid Intervention Study (JELIS) used a highly purified, fish oil extract containing only eicospentaenoic acid (EPA) and showed a reduction in cardiovascular events.3 This led to the large, randomised, double-blind, placebo-controlled, multinational trial called the Reduction of Cardiovas

An extended version of this paper  is available in the downloadable PDFs (see right hand column) to registered users. Registration to the website is free of charge. Introduction Patients with type 2 diabetes mellitus (T2DM) have a two- to four-fold increased risk for cardiovascular disease (CVD) compared with individuals without T2DM.1 A dyslipidaemia pattern of increased levels of triglyceride (TG)-rich particles, and TG enrichment of high- and low-density lipoprotein (HDL and LDL) is common in patients with T2DM, affecting nearly all lipid and lipoprotein variables.2 As a result, dyslipidaemia in patients with T2DM is characterised by el