Tag Archives: type 2 diabetes mellitus

Introduction Dr Tobias MacCarthy In 1736, Benjamin Franklin declared that ‘an ounce of prevention is worth a pound of cure’. With an ever-growing incidence of obesity, diabetes and cardiovascular disease, compounded by overwhelmed health services, this principle remains central to healthcare policies today. Diabetes has long been known to be associated with cardiovascular disease, principally heart failure, and the two are interlinked through mechanisms including increased oxidative stress, which leads to myocardial inflammation and fibrosis. There is now increasing focus on the concept of the ‘metabolic syndrome’ as an umbrella term

An extended version of this paper  is available in the downloadable PDFs (see right hand column) to registered users. Registration to the website is free of charge. Introduction Patients with type 2 diabetes mellitus (T2DM) have a two- to four-fold increased risk for cardiovascular disease (CVD) compared with individuals without T2DM.1 A dyslipidaemia pattern of increased levels of triglyceride (TG)-rich particles, and TG enrichment of high- and low-density lipoprotein (HDL and LDL) is common in patients with T2DM, affecting nearly all lipid and lipoprotein variables.2 As a result, dyslipidaemia in patients with T2DM is characterised by el