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Tag Archives: antibiotics

September 2021 Br J Cardiol 2021;28:98–101 doi:10.5837/bjc.2021.038

Outpatient parenteral antimicrobial therapy (OPAT) service is associated with inpatient-bed cost savings

Chun Shing Kwok, Joanna J Whittaker, Caroline Malbon, Barbara White, Jonathan Snape, Vikki Lloyd, Farah Yazdani, Timothy Kemp, Simon Duckett

Abstract

Introduction A major contributor to the cost of a patient’s care is the number of days occupying hospital beds. In a cardiology department, there are some patients that require long-term antibiotics, such as those with infective endocarditis or infected prosthetic devices. While most of these high-risk patients require some duration of monitoring for complications and deterioration as inpatients, there are patients who may, after a period of observation, be stable enough to be discharged home with outpatient intravenous therapy. In this report, we describe our experience with intravenous antibiotic therapy for patients with cardiology diagn

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British Heart Valve Society update: a change in the NICE guidelines on antibiotic prophylaxis

August 2016 Br J Cardiol 2016;23:91–2 doi:10.5837/bjc.2016.027

British Heart Valve Society update: a change in the NICE guidelines on antibiotic prophylaxis

John B Chambers, Martin H Thornhill, Mark Dayer, David Shanson

Abstract

This change followed approaches to Sir Andrew Dillon by the widow of a patient with a replacement aortic valve who died from infective endocarditis (IE) developing after unprotected dental scaling. Her case included: evidence that antibiotic prophylaxis is effective in people at high risk of IE having high-risk dental procedures;3 the observation that the incidence of IE in the UK has accelerated above the global background rise since the original 2008 NICE guidance;4 a change in the law on consent.5-7  It is now necessary for dentists to appraise their patient of the differences between NICE and other guidelines, if it is likely that they

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August 2015 Br J Cardiol 2015;22:101–4 doi:10.5837/bjc.2015.029

Inflammation is associated with myocardial ischaemia

Kushal Pujara, Ashan Gunarathne, Anthony H Gershlick

Abstract

Introduction Coronary heart disease (CHD) is the leading cause of death worldwide. Chronic subclinical inflammation is a key recognised process in the pathogenesis of CHD, and may play an important role in atherogenesis. Figure 1. Atherosclerotic plaque rupture Atherosclerosis is a complex multi-factorial disease process, which is initiated at the endothelium in response to various forms of injurious stimuli (shear stress, oxidative stress, arterial pressure changes) including inflammation. These factors appear to alter the endothelial cell’s capacity to maintain homeostasis and vascular tone and leads to the so-called endothelial ‘dysfun

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February 2015 Br J Cardiol 2015;22:11 Online First

Correspondence: don’t see their heart broken

Mervyn Huston

Abstract

Dear Sirs, There has been much debate regarding the prophylactic prescribing of antibiotics in patients deemed at risk of developing infective endocarditis (IE) as a result of certain dental procedures.1 The National Institute for Health and Care Excellence (NICE), the British Society for Antimicrobial Chemotherapy (BSAC) and the American Heart Association (AHA) have produced differing guidelines for dental practitioners, who may decide to accept one particular code entirely, or a modified version based on discussion with local cardiology departments. This culture of debate amongst cardiologists, dentists and patients regarding best interest,

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