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Tag Archives: atherosclerotic cardiovascular disease

October 2019 Br J Cardiol 2019;26:137–40 doi:10.5837/bjc.2019.036 Online First

PCSK9 inhibitors in familial hypercholesterolaemia: a real-world experience and a meta-analysis

Harshal Deshmukh, Deepa Narayanan, Maria Papageorgiou, Yvonne Holloway, Sadaf Ali, Thozhukat Sathyapalan

Abstract

Introduction Familial hypercholesterolaemia (FH) is a monogenic disorder characterised by excessive levels of low-density lipoprotein-cholesterol (LDL-C) and associated with significant cardiovascular morbidity and mortality.1 A reduction in LDL-C levels is the mainstay of treatment in FH and evidence-based guidelines have proposed treatment goals for these patients. The National Institute for Health and Care Excellence (NICE) recommends at least a 50% reduction in LDL-C levels from the baseline measurement in patients with FH,2 while the European Atherosclerosis Society and the International FH Foundation suggest target LDL-C levels of <2

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November 2018 Br J Cardiol 2018;25:133

In brief

BJC Staff

Abstract

Self-monitoring of type 2 diabetes cuts costs Self-monitoring of type 2 diabetes used in combination with an electronic feedback system results in considerable savings on health care costs and also travel costs for patients, especially in sparsely populated areas, a new study shows. The study, carried out in Northern Karelia by the University of Eastern Finland, found that by replacing half of the required follow-up visits for type 2 diabetes with self-measurements and electronic feedback, total costs of glycated haemoglobin monitoring were reduced by nearly 60%. The annual per-patient cost was down from 280 euros to 120 euros. Fewer follow-u

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Treatment patterns and lipid levels among patients with high-risk atherosclerotic CVD in the UK

October 2015 Br J Cardiol 2015;22:147–54 doi:10.5837/bjc.2015.034 Online First

Treatment patterns and lipid levels among patients with high-risk atherosclerotic CVD in the UK

Beth L Nordstrom, Jenna M Collins, Robert Donaldson, William A Engelman, Antje Tockhorn, Yajun Zhu, Zhenxiang Zhao

Abstract

Introduction Atherosclerotic cardiovascular disease (ASCVD), including peripheral arterial disease (PAD), coronary artery disease (CAD), acute coronary syndrome (ACS), and cerebrovascular disease (CeVAD), together account for approximately half of the morbidity and mortality in the adult population of Europe aged 50 years and older.1,2 The 2012 Coronary Heart Disease Statistics from the British Heart Foundation reported nearly 180,000 deaths in the UK from cardiovascular disease (CVD), 292 million prescriptions for CVD treatments, and over 87,000 percutaneous coronary interventions (PCIs) during a one-year span.3 In addition, diabetes mellitu

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