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Tag Archives: coronary computed tomography angiography (CCTA)

July 2022 Br J Cardiol 2022;29(3) doi:10.5837/bjc.2022.023

Age and the power of zero CAC in cardiac risk assessment: overview of the literature and a cautionary case

John P Sheppard, Suvasini Lakshmanan, Seth J Lichtenstein, Matthew J Budoff, Sion K Roy

Abstract

Introduction Since its inception by Agatston and Janowitz in 1990, coronary artery calcium (CAC) scoring has blossomed from a novel imaging tool to an internationally accepted biomarker of cardiovascular risk included in current preventive atherosclerotic cardiovascular disease (ASCVD) guidelines.1-7 With its growing adoption, debate has emerged over the proper use of CAC scores in risk stratification, with controversy surrounding its role in excluding obstructive disease in symptomatic patients. Presently, we focus on the role of CAC in risk stratification for coronary heart disease (CHD). We review the overwhelming evidence validating CAC

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