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Tag Archives: coronavirus

October 2020 Br J Cardiol 2020;27(4) doi:10.5837/bjc.2020.031

Neprilysin inhibitors and angiotensin(1–7) in COVID-19

Nathalie Esser, Sakeneh Zraika

Abstract

The issue regarding use of RAS blockers in the context of COVID-19 has previously been reviewed.1,2 Most recently, emerging data suggest no harm is associated with use of ACE inhibitors or ARBs in COVID-19.3,4 In this perspective, we discuss a related aspect that was first raised by Acanfora and colleagues,5 namely, the potential benefit of neprilysin inhibitors and their role in modulating levels of RAS components. Similar to the situation for ACE inhibitors and ARBs, it seems there are mixed opinions on the utility of neprilysin inhibitors in COVID-19. In a recent review, it was postulated that increasing neprilysin activity might mitigate

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June 2020 Br J Cardiol 2020;27:49 doi:10.5837/bjc.2020.016

Catheter lab activity and COVID-19: damned if you do and…

Nick Curzen

Abstract

Professor Nick Curzen Consensus statement In response to the need for guidance and clarity, national consensus statements have been published as a consensus between the British Cardiovascular Society, the British Cardiovascular Intervention Society (BCIS), NHS England/Public Heath England and the Heart Rhythm Society (in the case of the PPE document). The rationale and considerations behind these statements is discussed more fully elsewhere.2 In brief, the guidance for the three contentious areas listed above is summarised as follows. Firstly, the recommendation was that the default treatment for STEMI in the UK should remain primary PCI, unl

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