Tag Archives: diuretics

25in25 The meeting began with an update on the 25in25 initiative from BSH Chair-Elect Dr Lisa Anderson (St George’s University Hospital, London). This national quality improvement initiative, led by the BSH in collaboration with over 54 national and international healthcare organisations, has the goal of reducing heart failure deaths by 25% over the next 25 years. With already over one million people in the UK living with heart failure, a number which is expected to double by 2040, the ambitious initiative is eagerly awaited. In the UK alone this could translate to over 10,000 lives saved per year. A population health approach underpins th

Introduction It is estimated that about 920,000 people are living with heart failure (HF) in the UK.1 According to a National Heart Failure Audit (NHFA) summary report, 74,696 patients were admitted to hospitals in England and Wales due to heart failure between April 2018 and March 2019, representing a 21% rise from a year ago.2 Acute heart failure (AHF) has high mortality of 9.3%,2 and the morbidity is also substantial, including depression and hopelessness.3 Psychological intervention in the form of cognitive behavioural therapy improved quality of life in patients with HF and also led to a reduction in the exploratory outcome of rehospita

The patients who developed cardiotoxicity were treated with beta blockers (carvedilol), angiotensin-converting enzyme inhibitors (enalapril) or angiotensin receptor blockers (valsartan), aldosterone antagonists (eplerenone), digitalis and diuretics (furosemide), as needed. When patients remained symptomatic and met the PARADIGM-HF inclusion criteria, sacubitril/valsartan was started instead of enalapril or valsartan. Results showed that sacubitril/valsartan therapy produced an improvement in ventricular remodelling, diastolic dysfunction, and on symptoms, reflected in the New York Heart Association class and the six-minute walk test. The auth

Introduction Acute heart failure (AHF) syndromes are the leading cause of hospitalisation in patients over 65 years of age in the UK, accounting for 67,000 admissions per year.1 The immediate management of AHF focuses on symptom relief and stabilisation of the patient’s haemodynamic profile – traditionally achieved with a combination of oxygen, diuretics and nitrate therapy.1-5 Recent guidelines from the National Institute for Health and Care Excellence (NICE),1 and the European Society of Cardiology (ESC),5 have highlighted the poor-quality evidence base for many of these interventions.3,4,6 The ESC guidelines (updated in 2016) state th

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Optimising care UK hospitals should set up acute heart failure units to help raise standards of care, according to Professor Henry Dargie (Golden Jubilee National Hospital, Glasgow). Presenting the inaugural Philip Poole-Wilson memorial lecture (see box), Professor Dargie said that there have been great improvements in heart failure treatment, with effective drugs, devices and interventions, plus a multidisciplinary team approach. In addition, clinical trials have shown a 50% absolute reduction in heart failure mortality with modern treatments, proving what can be achieved with specialist care. But trial results are not being reproduced in c

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