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March 2010 Br J Cardiol 2009;17(Suppl 1):S10-11

Is dual antiplatelet therapy needed for all CVD patients?

Ranil de Silva

Abstract

Dual antiplatelet therapy for all CVD patients? Table 1. Currently used antiplatelet drugs Currently used antiplatelet drugs are summarised in table 1 and pivotal clinical trials of dual antiplatelet therapy in table 2. The Clopidogrel for High Atherothrombotic Risk and Ischaemia Stabilisation, Management and Avoidance (CHARISMA) trial2 is the only prospective randomised clinical trial to evaluate the efficacy and safety of dual antiplatelet therapy in all CVD patients. Initiated after the Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events (CAPRIE) trial had shown a 9% relative risk reduction with clopidogrel compared w

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