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Tag Archives: extended-release niacin/laropiprant

February 2011 Br J Cardiol 2011;18:37-45

Efficacy and safety of extended-release niacin/laropiprant in patients with type 2 diabetes mellitus

Alexandra MacLean, James M McKenney, Russell Scott, Eliot Brinton, Harold E Bays, Yale B Mitchel, John F Paolini, Hilde Giezek, Kristel Vandormael, Rae Ann Ruck, Kendra Gibson, Christine McCrary Sisk, Darbie L Maccubbin

Abstract

An extended version of this paper  is available in the downloadable PDFs (see right hand column) to registered users. Registration to the website is free of charge. Introduction Patients with type 2 diabetes mellitus (T2DM) have a two- to four-fold increased risk for cardiovascular disease (CVD) compared with individuals without T2DM.1 A dyslipidaemia pattern of increased levels of triglyceride (TG)-rich particles, and TG enrichment of high- and low-density lipoprotein (HDL and LDL) is common in patients with T2DM, affecting nearly all lipid and lipoprotein variables.2 As a result, dyslipidaemia in patients with T2DM is characterised by el

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