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Mild hyponatraemia and short-term outcomes in patients with heart failure in the community

June 2011 Br J Cardiol 2011;18:133–7

Mild hyponatraemia and short-term outcomes in patients with heart failure in the community

Sudip Ghosh, Jude Smith, Jonathan Dexter, Colette Carroll-Hawkins, Noel O’Kelly

Abstract

Introduction Hyponatraemia is a common electrolyte disorder among patients with heart failure (HF), nephrotic syndrome or cirrhosis.1-3 It is recognised as a predictor of adverse outcomes in hospitalised patients with these conditions,4-5 and its prognostic implications are commonly attributed to the severity of the underlying pathology. Patients admitted to hospital with decompensated heart failure have a poor prognosis, with in-hospital mortality rates approaching 10%.5-7 Hyponatraemia associated with decompensation results in added adverse outcomes resulting in high 30–90-day mortality and re-hospitalisation rates.5-9 These results have

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