Tag Archives: hypothyroidism

Background Hypothyroidism is a common endocrine disorder, which has a variety of effects on the cardiovascular system including decreased cardiac output, increased systemic vascular resistance, accelerated atherosclerosis and rhythm disturbances, such as sinus bradycardia, conduction defects or non-specific ST changes.1,2 Hypothyroidism can also cause prolongation of the QTc interval and ventricular arrhythmias.1 Case presentation A 76-year-old woman was admitted to our hospital with a collapse, and while in the emergency department she sustained a witnessed cardiac arrest secondary to torsades de pointes (TdP) (figure 1). This was terminated

Table 1: Selection of treatments in pulmonary arterial hypertension (PAH) It is very difficult to select PAH treatments, said Professor Hoeper, as there are only limited data to provide guidance. However, a number of factors are taken into consideration and these are shown in table 1. Since many patients are being treated with combinations, the possibility of drug-drug interactions increases.3 Similarly, the mode and convenience of administration must be considered; for example many patients might prefer oral administration. Treatment costs and approval status are also considerations. There are disparities in the indications for these drugs

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