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Tag Archives: intravenous iron therapy

September 2026 Br J Cardiol 2026;33:102–7 doi:10.5837/bjc.2026.042

Ironing out the details: a comprehensive review of iron therapy in heart failure

Ravi Chotalia, Yasir Bakhit, Minesh Chotalia, Shirley Sze

Abstract

Introduction Heart failure (HF) is a clinical syndrome characterised by signs and symptoms that result from reduced cardiac output and/or elevated cardiac pressures. The European Society of Cardiology (ESC) classifies HF by left ventricular (LV) ejection fraction (EF) into reduced (HFrEF; LVEF <40%), mildly reduced (HFmrEF; LVEF 41–49%) and preserved (HFpEF; LVEF ≥50%).1 Iron is an essential micronutrient involved in systemic oxygen delivery and utilisation. Iron deficiency (ID) can either result from depleted iron stores (absolute ID) or impaired iron usage despite normal stores (functional ID) and can exist in the absence of anaemia.

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