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February 2021 Br J Cardiol 2021;28(suppl 1):S7–S9 doi:10.5837/bjc.2021.s02

United Kingdom treatment of iron deficiency in heart failure: are we missing opportunities?

Chun Shing Kwok, Sarah McDermott, Sadie Bennett, Simon Duckett

Abstract

Introduction Iron deficiency in patients with heart failure with reduced ejection fraction (HFrEF) is common, affecting 60% of patients with hospitalisation for heart failure or worsening heart failure in the outpatient setting.1 Patients with heart failure are iron deficient for multiple reasons, including poor nutrition, malabsorption, reduced intracellular uptake of iron and blood loss.2 Two meta-analyses of randomised-controlled trials (RCTs) have shown the benefits of restoring iron levels in improving quality of life, exercise tolerance and reducing hospitalisation for heart failure, although, as of yet, no mortality benefit has been se

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