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Contrast-induced nephropathy in PCI: an evidence-based approach to prevention

February 2015 Br J Cardiol 2015;22:34 doi:10.5837/bjc.2015.001 Online First

Contrast-induced nephropathy in PCI: an evidence-based approach to prevention

Asad Shabbir, Jamie Kitt, Omar Ali

Abstract

Pathogenesis With the advent of the iodinated contrast study came the complication of contrast-induced nephropathy (CIN), an increasingly recognised and discussed iatrogenic disease process seen with coronary angiography. As we become more invasive in our cardiac investigations, and coronary interventions become more widespread, coronary angiography is offered to more and more patients. Therefore, a better understanding of the treatment modalities aimed at minimising the risk of CIN has never been more important. Figure 1. Aetiology of contrast-induced nephropathy CIN is a direct hyper-acute tubular insult on the filtering mechanisms of the k

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