September 2010 Br J Cardiol 2010;17:207–08
Khaled Alfakih, Mathew Budoff
MDCT coronary angiography (CTCA) has been shown to be highly accurate at detecting coronary artery disease (CAD) with more than 30 studies and several meta-analyses confirming excellent sensitivity and negative predictive value (NPV), when compared with invasive X-ray coronary angiography.1 This was confirmed in three multi-centre trials: Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography (ACCURACY) (n=230), Coronary Artery Evaluation Using 64-Row Multi-detector Computed Tomography Angiography (CORE-64) (n=291), and Meijboom et al. (n=360)2-4 (table 1). The positive predictive value
February 2010 Br J Cardiol 2010;17:40-3
Nevin T Wijesekera, Simon P G Padley, Gonzalo Ansede, Robert P Barker, Michael B Rubens
Introduction Very elderly individuals are the fastest growing segment of most Western populations, with those aged 80 and older projected to triple in number by the middle of this century.1,2 The prevalence of coronary artery disease is high in this age group, and diagnostic investigations are being used with increasing frequency when angina is poorly controlled by medical therapy. However, due to more extensive disease and less functional reserve, invasive investigations have a higher complication rate in the very elderly than in younger patients.3 Therefore, non-invasive tests that identify those patients most likely to benefit from invasiv
July 2009 Br J Cardiol 2009;16:199–200
Edward T D Hoey, Nicholas J Screaton, Bobby S K Agrawal, Matthew J Daniels, Andrew A Grace, Deepa Gopalan
At age 16, he started to suffer with recurrent attacks of pre-syncope and a 24-hour tape documented runs of broad complex tachycardia for which he was commenced on sotalol and fitted with a single-chamber rate-responsive pacing system. Electrocardiogram (ECG) on admission showed an unusual pattern of right bundle branch block, extreme left axis deviation and first-degree heart block. Transthoracic echocardiogram demonstrated biventricular dilatation, moderately impaired left ventricular systolic function and prominent trabeculations, which raised the suspicion of left ventricular non-compaction (LVNC). Interestingly, his twin brother also had
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